Case overview

A 63-year-old, male patient with progressive exertional dyspnoea lasting for 2 years and dry cough showed a mild reduction of DLCO at initial lung function testing. An initial HRCT revealed a possible UIP pattern including reticular abnormalities and traction bronchiectasis. Functional follow-up testing showed preserved FVC despite progressive reduction in DLCO.
This is a case that shows that preserved lung volumes do not exclude IPF even in the absence of emphysema. Also, DLCO deterioration seems to correlate better with progression of fibrosis on HRCT.