HRCT shows a possible UIP pattern with:
- Traction bronchiectasis (minimal)
- Centrilobular emphysema
- Paraseptal emphysema / DD honeycombing
- Reticulation (only around emphysema)
The differential diagnosis of a UIP pattern remains difficult and sometimes cannot be “solved”.
In some situations a paraseptal emphysema is very difficult to distinguish from honeycombing. In these cases searching for coincidence with centrilobular emphysema could be helpful.
- Raghu, et al. An official ATS/ERS/JRS/ALAT Statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med. 2011 Mar 15;183(6):788-824.