Differential diagnosis

The MSCT shows signs of emphysema and pulmonary fibrosis with possible UIP pattern, i.e. combined pulmonary fibrosis and emphysema
The differential diagnosis includes the following:
  • Idiopathic interstitial pneumonia with emphysema, ie. CPFE
  • Connective tissue disease-associated CPFE
  1. Cottin V, et al. Combined pulmonary fibrosis and emphysema syndrome in connective tissue disease. Arthritis Rheum. 2011;63(1):295-304.
  2. Cottin V. The impact of emphysema in pulmonary fibrosis. Eur Respir Rev. 2013;22(128):153-157.
Provided by Prof. Heussel and PD Kreuter (Thoraxklinik Heidelberg, Germany)